After completion, Rufus will ask you to restart the PC.Now, click on the Start button and wait for a while to finish.Make sure to keep all the default settings as it is.Now, open Rufus, in order to create bootable media for Windows 10.Now follow the following steps to clean install Windows 10 using ISO file, If you have your Windows 10 ISO File ready to update your system to Windows 10 Latest Update, all you have to do is boot from the disc or USB thumb drive to start the setup. 64-Bit Install Windows 7 ISO (Clean Install)